Sanarever®

Soy and its peptides show excellent anti-inflammatory, anti-bacterial, and anti-oxidant properties. Soy protein offers a safe alternative to animal protein and endogenous estrogen in promoting superficial wound healing. Fermented soybean provides microbiome balance. Cryptic peptides in it accelerate the synthesis of the skin’s ECM, and activate the skin’s re epithelization to promote wound healing. This ECM mimicking action of these peptides stimulates tissue regeneration by promoting cell adhesion, generation, and migration. Moreover, soy has phytoestrogens that speed up the healing process through the estrogen receptor signaling pathway.

Probiotics are nonpathogenic “good microbes” that accelerate the wound healing process. They work in a host friendly and mechanical way by inhibiting, pushing back, and replacing pathogens so that there is no more pathogenic activity in the lesion. Probiotics help prevent the aggregation and biofilm formation of bacteria. This way, they eliminate the need for antibiotics and prevent harmful bacterial mutation.

Some studies have shown that a mixture of probiotic strains is more effective than the single one. The reason may be a synergistic interaction between the strains in the mixture or due to the higher dose of probiotics. Based on this concept, Sanarever® is sourced from a perfect blend of 16 species of probiotics fermented with soybean. We carefully selected species and the number of our probiotics since both make a huge difference.

Fermentation is the oldest biotechnology tool that uses microorganisms to bring about a chemical change. To take it to the next level, we have taken advantage of the symbiotic interaction of bacteria to produce fermented peptides. We have experimented for 11 years to learn how to let them produce effective anti-bacterial peptides and symbiotics together. We make use of symbiotic fermentation through probiotics and soybean to enable wound healing.

Postbiotics, are the main focus of our primary product. They are functional bio active products of probiotic metabolism that have excellent excellent anti-inflammatory, immunomodulatory, and bactericidal properties, all of which together with their angiogenesis effects accelerate wound healing. Postbiotics promote the growth of natural probiotics in the human digestive system. A thin film of postbiotics modulates the inflammatory phase, stimulates the development of new blood vessels, and increases collagen and elastin production to improve wound healing.

Allantoin is found in several plants, such as the sugar beet, comfrey, chamomile, and wheat sprouts. Allantoin is the active ingredient in Sanarever® skin protectant spray. This skin active ingredient is approved by the FDA monograph for use as a skin protectant and wound healing ingredient. It promotes the lesion’s transition from an inflammatory to a proliferative state. Allantoin has excellent anti-inflammatory, anti-oxidant, karyolitic, soothing, moisturizing, and anti irritant properties all of which accelerate wound healing by promoting the renewal of epidermal cells. Allantoin is safe and non-irritant, highly compatible with the skin. 

Aloe Vera has been used for years to treat chronic wounds, burns, and skin irritation. It is a super effective antibacterial and antiseptic ingredient that promotes wound healing by changing the amount and composition of collagen in the wound. It further increases the amount of collagen and promotes cross linking in its structure. Aloe gel also stimulates the proliferation and migration of fibroblasts and keratinocytes to heal the wound. Additionally, Aloe Vera contains various amino acids, mucopolysaccharides, and zinc that provide skin integrity, help retain moisture in it, reduce erythema, and prevent skin ulcers.